SCHEMBL10896142

SCHEMBL10896142

CCCCC[C@H]1CC[C@H]([C@H]2CC[C@H](c3ccc([C@H]4CC[C@H]([C@H]5CC[C@H](CCCCC)CC5)CC4)cc3)CC2)CC1

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.50
MAPT P10636 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
ALDH1A1 P00352 1/20 0.48
LMNA P02545 1/20 0.48
MAPK1 P28482 1/20 0.48
SPHK1 Q9NYA1 11/20 0.47
ESR2 Q92731 2/20 0.46
GAA P10253 1/20 0.43
SPHK2 Q9NRA0 7/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10893963 1.00 CYP2C9 (0.50) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL10893968 1.00 CYP2C9 (0.50) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL10579686 0.94 CYP2C9 (0.54) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL9399116 0.94 CYP2C9 (0.54) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL10891958 0.94 ESR2 (0.46) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL10760223 0.94 CYP2C9 (0.46) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL10891955 0.94 ESR2 (0.46) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL10760219 0.94 CYP2C9 (0.46) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL10891950 0.94 ESR2 (0.46) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL10891962 0.94 ESR2 (0.46) CYP2C9MAPTMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0084974-B1 CARBOCYCLIC COMPOUNDS WITH LIQUID-CRYSTAL PROPERTIES Chisso Corporation (JP) 1986-04-02 EP disclosed
US-4477369-A New high temperature liquid-crystalline substances consisting of 4 or 5 six-member-rings and liquid-crystalline compositions containing same CHISSO CORPORATION (JP) 1984-10-16 US disclosed
EP-0084974-A1 Carbocyclic compounds with liquid-crystal properties Chisso Corporation (JP) 1983-08-03 EP disclosed