SCHEMBL10896358

SCHEMBL10896358

CC1CCC2(CCC(=O)CC2)CC1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.32
CRBN Q96SW2 1/20 0.32
MEN1 O00255 1/20 0.31
CYP2C9 P11712 1/20 0.31
KMT2A Q03164 1/20 0.31
CA1 P00915 2/20 0.30
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20659703 0.86 ESR2 (0.31) ESR2CRBN
SCHEMBL9171769 0.79 TRIM24 (0.44) CRBNMEN1CYP2C9KMT2A
SCHEMBL24309070 0.79 KDM4E (0.32)
SCHEMBL7343703 0.76 ESR2 (0.32) ESR2MEN1CYP2C9KMT2A
SCHEMBL307414 0.76
SCHEMBL3021931 0.76
SCHEMBL16099106 0.76 TRIM24 (0.41) CRBNMEN1CYP2C9KMT2A
SCHEMBL17611832 0.76 DPP4 (0.35)
SCHEMBL27836649 0.73 CRBN (0.41) ESR2CRBNKMT2ACA1CA2
SCHEMBL104009 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0074693-B1 PERFUME COMPOSITIONS AND PERFUMED ARTICLES CONTAINING SPIRO-UNDECANONES AND -UNDECENONES AS PERFUME BASE NAARDEN INTERNATIONAL N.V. (NL) 1986-01-08 EP disclosed
US-4448712-A Perfume compositions and perfumed articles containing spiro-undecanones and -undecenones as perfume base NAARDEN INTERNATIONAL N.V. (NL) 1984-05-15 US disclosed
EP-0074693-A1 Perfume compositions and perfumed articles containing spiro-undecanones and -undecenones as perfume base NAARDEN INTERNATIONAL N.V. (NL) 1983-03-23 EP disclosed