SCHEMBL10896450

SCHEMBL10896450

Cc1ccc(CN2CCSC2=NC#N)cc1

nearest known ligand 0.67

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.67
CHRNA7 P36544 1/20 0.67
KMT2A Q03164 1/20 0.67
TDP1 Q9NUW8 1/20 0.67
PDE4B Q07343 14/20 0.65
PDE4D Q08499 6/20 0.52
HTT P42858 1/20 0.46
MAPT P10636 2/20 0.40
TP53 P04637 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10896446 1.00 MEN1 (0.67) MEN1CHRNA7KMT2ATDP1PDE4B
SCHEMBL10896891 0.87 MEN1 (0.72) MEN1CHRNA7KMT2ATDP1PDE4B
SCHEMBL13596875 0.87 MEN1 (0.72) MEN1CHRNA7KMT2ATDP1PDE4B
SCHEMBL10897934 0.86 MEN1 (0.67) MEN1CHRNA7KMT2ATDP1PDE4B
SCHEMBL10897929 0.86 MEN1 (0.67) MEN1CHRNA7KMT2ATDP1PDE4B
SCHEMBL25003079 0.85 MEN1 (0.66) MEN1CHRNA7KMT2ATDP1PDE4B
SCHEMBL9818810 0.85 MEN1 (0.66) MEN1CHRNA7KMT2ATDP1PDE4B
SCHEMBL9818814 0.85 MEN1 (0.66) MEN1CHRNA7KMT2ATDP1PDE4B
SCHEMBL10894675 0.85 PDE4B (0.67) MEN1CHRNA7KMT2ATDP1PDE4B
SCHEMBL10894672 0.85 PDE4B (0.67) MEN1CHRNA7KMT2ATDP1PDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4616025-A ANTIULCER AGENTS RICHTER GEDEON VEGYESZETI GYAR RT (HU) 1986-10-07 US disclosed