Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TERT | O14746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1130982 | 0.81 | PREP (0.44) | PREPCYP1A2TRPA1KDM4ETNKS | |
| SCHEMBL13585026 | 0.80 | PREP (0.41) | PREPCYP1A2NPC1RAB9ATNKS | |
| SCHEMBL13585023 | 0.80 | PREP (0.41) | PREPCYP1A2NPC1RAB9ATNKS | |
| SCHEMBL15208775 | 0.78 | OTC (0.44) | PREPTGM2 | |
| SCHEMBL15208779 | 0.78 | OTC (0.44) | PREPTGM2 | |
| SCHEMBL10750976 | 0.77 | PREP (0.40) | PREPTSHRTRPA1KDM4ETNKS | |
| SCHEMBL15201380 | 0.77 | PREP (0.45) | PREPTRPA1RAB9ATNKSMCL1 | |
| SCHEMBL13585603 | 0.76 | PREP (0.42) | PREP | |
| SCHEMBL13585608 | 0.76 | PREP (0.42) | PREP | |
| SCHEMBL3562992 | 0.76 | CD274 (0.55) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596813-A | Pyridylcarbonyl and thiocarbonyl derivatives useful as fungicides | CHEVRON RESEARCH COMPANY (US) | 1986-06-24 | — | — | US | disclosed |