Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 3/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10899658 | 1.00 | PREP (0.51) | PREPACE2KMT2AGFERCTRB1 | |
| SCHEMBL13567881 | 0.89 | PREP (0.52) | PREPACE2KMT2AGFERCTRB1 | |
| SCHEMBL10903868 | 0.86 | KMT2A (0.45) | PREPACE2KMT2AGFERCTRB1 | |
| SCHEMBL4977446 | 0.86 | PREP (0.53) | PREPACE2KMT2AGFERNPSR1 | |
| SCHEMBL13567882 | 0.86 | PREP (0.47) | PREPACE2GFERNPSR1TSHR | |
| SCHEMBL791439 | 0.85 | PREP (0.57) | PREPACE2KMT2AGFERNPSR1 | |
| SCHEMBL13994810 | 0.85 | PREP (0.57) | PREPACE2KMT2AGFERNPSR1 | |
| SCHEMBL1122261 | 0.85 | PREP (0.55) | PREPACE2KMT2AGFERCTRB1 | |
| SCHEMBL1122258 | 0.85 | PREP (0.55) | PREPACE2KMT2AGFERCTRB1 | |
| SCHEMBL15607552 | 0.84 | ACE2 (0.55) | PREPACE2GFERNPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596819-A | Antidepressive agents | WARNER-LAMBERT COMPANY (US) | 1986-06-24 | — | — | US | claimed |
| US-4596819-A | Antidepressive agents | WARNER-LAMBERT COMPANY (US) | 1986-06-24 | — | — | US | disclosed |