SCHEMBL1090022

SCHEMBL1090022

CCO[Si](CCC1CCC2OC2C1)(OCC)OCC.CO[Si](C)(CCC1CCC2OC2C1)OC

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6755355 0.92 PTGS1 (0.32) PTGS1PTGS2
SCHEMBL23061486 0.91 PTGS1 (0.32) PTGS1PTGS2
SCHEMBL20478203 0.91 PTGS1 (0.32) PTGS1PTGS2
SCHEMBL14715756 0.91 PTGS1 (0.32) PTGS1PTGS2
SCHEMBL14715755 0.91 PTGS1 (0.32) PTGS1PTGS2
SCHEMBL48916 0.91 PTGS1 (0.32) PTGS1PTGS2
SCHEMBL3294819 0.90 PTGS1 (0.32) PTGS1PTGS2
SCHEMBL3300369 0.90 PTGS1 (0.32) PTGS1PTGS2
SCHEMBL6424775 0.90 PTGS1 (0.32) PTGS1PTGS2
SCHEMBL2363758 0.90 PTGS1 (0.31) PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2064257-B1 SOLID POLYMERIC SUBSTRATE HAVING ADHERENT RESIN COMPONENT DERIVED FROM CURABLE SILYLATED POLYURETHANE COMPOSITION MOMENTIVE PERFORMANCE MAT INC (US) 2017-10-18 EP disclosed
US-8153261-B2 Hydroxyl-terminated polyurethane prepolymer, an isocyanatosilane and a filler, UV stabilizer, antioxidant, catalyst, adhesion promoter, cure accelerator, thixotropic agent, plasticizer, moisture scavenger, pigment, dye, surfactant, defoamer, solvent or biocide MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-04-10 US disclosed
EP-2064257-A2 SOLID POLYMERIC SUBSTRATE HAVING ADHERENT RESIN COMPONENT DERIVED FROM CURABLE SILYLATED POLYURETHANE COMPOSITION Momentive Performance Materials Inc. (US) 2009-06-03 EP disclosed
WO-2008027499-A2 SOLID POLYMERIC SUBSTRATE HAVING ADHERENT RESIN COMPONENT DERIVED FROM CURABLE SILYLATED POLYURETHANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-03-06 WO disclosed
US-20080057316-A1 Solid polymeric substrate having adherent resin component derived from curable silylated polyurethane composition GENERAL ELECTRIC COMPANY (US) 2008-03-06 US disclosed