Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | GNPAT | O15228 | 1/20 | 0.46 |
| ▸ | GSR | P00390 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10900479 | 1.00 | FOLH1 (0.48) | FOLH1GNPATGSRDPP8DPP9 | |
| SCHEMBL30731554 | 0.96 | FOLH1 (0.48) | FOLH1GNPATGSRDPP8DPP9 | |
| SCHEMBL29886743 | 0.95 | FOLH1 (0.52) | FOLH1GNPATGSRDPP8DPP9 | |
| SCHEMBL29887771 | 0.95 | FOLH1 (0.52) | FOLH1GNPATGSRDPP8DPP9 | |
| SCHEMBL30924954 | 0.95 | GSR (0.49) | FOLH1GSRDPP8DPP9DPP7 | |
| SCHEMBL30242742 | 0.93 | GSR (0.50) | FOLH1GNPATGSRDPP8DPP9 | |
| SCHEMBL30414807 | 0.93 | GSR (0.50) | FOLH1GNPATGSRDPP8DPP9 | |
| SCHEMBL29839281 | 0.93 | GSR (0.50) | FOLH1GNPATGSRDPP8DPP9 | |
| SCHEMBL29420697 | 0.93 | FOLH1 (0.53) | FOLH1GNPATGSRBACE1CTSD | |
| SCHEMBL3773039 | 0.92 | FOLH1 (0.55) | FOLH1GSRDPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4588684-A | a-Factor and its processing signals | CHIRON CORPORATION (US) | 1986-05-13 | — | — | US | disclosed |
| EP-0123289-A2 | A-factor and its processing signals | CHIRON CORPORATION (US) | 1984-10-31 | — | — | EP | disclosed |