Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31666382 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2CA12CA1CA2CA7 | |
| SCHEMBL25434306 | 0.92 | CA1 (0.61) | SMN1; SMN2CA12CA1CA2CA7 | |
| SCHEMBL151213 | 0.92 | CA1 (0.61) | SMN1; SMN2CA12CA1CA2CA7 | |
| SCHEMBL27753904 | 0.92 | CA1 (0.61) | SMN1; SMN2CA12CA1CA2CA7 | |
| SCHEMBL27731704 | 0.89 | SMN1; SMN2 (0.58) | SMN1; SMN2CA12CA1CA2CA7 | |
| Bromide SCHEMBL28158222 | 0.89 | SMN1; SMN2 (0.58) | SMN1; SMN2CA12CA1CA2CA7 | |
| Ammonia Solution, Strong SCHEMBL4268652 | 0.89 | SMN1; SMN2 (0.58) | SMN1; SMN2CA12CA1CA2CA7 | |
| Hydrochloric Acid SCHEMBL31658961 | 0.89 | SMN1; SMN2 (0.58) | SMN1; SMN2CA12CA1CA2CA7 | |
| SCHEMBL8592328 | 0.87 | AR (0.50) | SMN1; SMN2CA12CA1CA2CA7 | |
| Bromide SCHEMBL1307432 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103393618-A | Pharmaceutical composition comprising 11-deoxy-prostaglandin compound and method for stabilizing same | R TECH UENO LTD | 2013-11-20 | — | — | CN | disclosed |
| US-4599423-A | Preparation of 5-(hydroxy- and/or aminophenyl-6-lower-alkyl)-2(1H)-pyridinones | STERLING DRUG INC. (US) | 1986-07-08 | — | — | US | disclosed |
| US-4465686-A | 5-(Hydroxy- and/or amino-phenyl)-6-(lower-alkyl)-2-(1H)-pyridinones, their cardiotonic use and preparation | STERLING DRUG INC. (US) | 1984-08-14 | — | — | US | disclosed |
| US-3960720-A | Gel product for separation purposes and method of using the product for hydrophobic salting out adsorption | EXPLOATERINGS AKTIEBOLAGET T.B.F. (SW) | 1976-06-01 | — | — | US | disclosed |