Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.76 |
| ▸ | MAPT | P10636 | 4/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.76 |
| ▸ | LMNA | P02545 | 3/20 | 0.76 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.76 |
| ▸ | TSHR | P16473 | 2/20 | 0.76 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.76 |
| ▸ | THPO | P40225 | 2/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.76 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.76 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.69 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.69 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.69 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7132512 | 0.90 | POLB (0.75) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9765716 | 0.90 | HIF1A (0.70) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11061948 | 0.88 | HIF1A (0.79) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10391478 | 0.87 | HIF1A (0.69) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10391543 | 0.87 | HIF1A (0.66) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9476417 | 0.87 | MEN1 (0.84) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| (R)-Nitrendipine SCHEMBL38973 | 0.87 | HIF1A (1.00) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| Nitrendipine SCHEMBL15516493 | 0.87 | HIF1A (1.00) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| (R)-Nitrendipine SCHEMBL30228952 | 0.87 | HIF1A (1.00) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| (S)-Nitrendipine SCHEMBL120983 | 0.87 | HIF1A (1.00) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4564619-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-14 | — | — | US | disclosed |