Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 18/20 | 0.74 |
| ▸ | CYSLTR1 | Q9Y271 | 18/20 | 0.74 |
| ▸ | PPARG | P37231 | 2/20 | 0.66 |
| ▸ | PPARD | Q03181 | 2/20 | 0.66 |
| ▸ | PPARA | Q07869 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.66 |
| ▸ | BLM | P54132 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10901977 | 0.95 | CYSLTR2 (0.79) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL10902667 | 0.94 | CYSLTR2 (0.73) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL10899700 | 0.94 | CYSLTR2 (0.73) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL10902027 | 0.91 | CYSLTR2 (0.90) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL10901953 | 0.91 | CYSLTR2 (0.90) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL10902043 | 0.91 | CYSLTR2 (0.90) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL10903838 | 0.89 | CYSLTR2 (0.77) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL10898584 | 0.89 | CYSLTR2 (0.89) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL10902148 | 0.89 | CYSLTR2 (0.89) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL10902944 | 0.89 | CYSLTR2 (0.89) | CYSLTR2CYSLTR1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4594442-A | Halogen containing alkoxy substitution | HOFFMAN-LA ROCHE INC. (US) | 1986-06-10 | — | — | US | disclosed |
| US-4539419-A | TREATMENT OF ALLERGIES | HOFFMANN-LA ROCHE INC. (US) | 1985-09-03 | — | — | US | disclosed |