Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 7/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 7/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PTGFR | P43088 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10903079 | 1.00 | TLR8 (0.43) | TLR8PTGER3PTGER2PTGER4PTGER1 | |
| SCHEMBL10617350 | 0.86 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1 | |
| SCHEMBL10482163 | 0.86 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1 | |
| SCHEMBL10482169 | 0.86 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1 | |
| SCHEMBL10383342 | 0.86 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1 | |
| SCHEMBL16154986 | 0.85 | APOBEC3G (0.38) | PTGER3PTGER2PTGER4PTGER1APOBEC3G | |
| SCHEMBL27892552 | 0.83 | TLR8 (0.44) | TLR8PTGER3PTGER2PTGER4PTGER1 | |
| SCHEMBL8206128 | 0.82 | TLR8 (0.51) | TLR8PTGER3PTGER2PTGER4PTGER1 | |
| SCHEMBL10904973 | 0.81 | TLR8 (0.43) | TLR8PTGER3PTGER2PTGER4PTGER1 | |
| SCHEMBL10904974 | 0.81 | TLR8 (0.43) | TLR8PTGER3PTGER2PTGER4PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4564476-A | Aryl fatty acid leukotriene synthesis inhibitors | MCNEILAB, INC. (US) | 1986-01-14 | — | — | US | disclosed |