Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP12 | P39900 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.31 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.31 |
| ▸ | OGA | O60502 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10903484 | 1.00 | CA9 (0.41) | CA9CA12CA1CA2MMP9 | |
| SCHEMBL7155715 | 0.88 | CA9 (0.38) | CA9CA12CA1CA2MMP9 | |
| SCHEMBL7155215 | 0.88 | CA9 (0.38) | CA9CA12CA1CA2MMP9 | |
| SCHEMBL7148709 | 0.86 | CA9 (0.39) | CA9CA12CA1CA2MMP9 | |
| SCHEMBL7148711 | 0.86 | CA9 (0.39) | CA9CA12CA1CA2MMP9 | |
| SCHEMBL18241580 | 0.86 | CA9 (0.39) | CA9CA12CA1CA2MMP9 | |
| SCHEMBL7155711 | 0.84 | CA9 (0.38) | CA9CA12CA1CA2MMP9 | |
| SCHEMBL16441832 | 0.81 | OGA (0.44) | CA9CA12CA1CA2MMP9 | |
| SCHEMBL7155210 | 0.81 | CA9 (0.35) | CA9CA12CA1CA2MMP9 | |
| SCHEMBL3238675 | 0.80 | CA9 (0.46) | CA9CA12CA1CA2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4572895-A | AQUEOUS NUTRIENT MEDIUM CONTAINING CARBOIN AND NITROGEN SOURCES; AEROBIC CONDITIONS | BRISTOL-MYERS COMPANY | 1986-02-25 | — | — | US | disclosed |
| US-4518589-A | BACTERICIDES, ANTITUMOR | BRISTOL-MYERS COMPANY (US) | 1985-05-21 | — | — | US | disclosed |