SCHEMBL10904670

SCHEMBL10904670

COC(C)C(=O)OC(C)Br

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1931602 0.79 TSHR (0.46) SMN1; SMN2TSHR
SCHEMBL11052245 0.76
SCHEMBL12046596 0.75 TSHR (0.36) SMN1; SMN2TSHR
SCHEMBL13342707 0.75 KMT2A (0.35) SMN1; SMN2TSHR
SCHEMBL12046587 0.75 TSHR (0.36) SMN1; SMN2TSHR
SCHEMBL2750798 0.75 TSHR (0.36) SMN1; SMN2TSHR
SCHEMBL13067170 0.75 KMT2A (0.35) SMN1; SMN2TSHR
SCHEMBL12046589 0.75 TSHR (0.36) SMN1; SMN2TSHR
SCHEMBL12046586 0.75 TSHR (0.36) SMN1; SMN2TSHR
SCHEMBL13038040 0.73 TSHR (0.35) SMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4602012-A Cephalosporin antibiotics GLAXO GROUP LIMITED (GB) 1986-07-22 US disclosed