SCHEMBL109052

SCHEMBL109052

C=CC(=O)OCCCCCNC

nearest known ligand 0.70

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.70
ALDH1A1 P00352 3/20 0.70
CYP3A4 P08684 1/20 0.70
HPGD P15428 1/20 0.58
TP53 P04637 2/20 0.48
HIF1A Q16665 2/20 0.48
HSD17B10 Q99714 1/20 0.48
THRB P10828 2/20 0.41
HCAR2 Q8TDS4 2/20 0.40
EPHX1 P07099 1/20 0.39
ATM Q13315 1/20 0.38
ACHE P22303 6/20 0.38
ZDHHC20 Q5W0Z9 1/20 0.38
ZDHHC2 Q9UIJ5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19333937 1.00 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
Hydrochloric Acid SCHEMBL28852507 0.98 TSHR (0.68) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL113045 0.98 TSHR (0.67) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL110329 0.92 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
Hydrochloric Acid SCHEMBL6053427 0.91 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
Trimethylammonium SCHEMBL27992106 0.86 TSHR (0.55) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL110438 0.84
SCHEMBL8493780 0.84 TSHR (1.00) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL322713 0.84 TSHR (1.00) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL9101988 0.84 TSHR (1.00) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2424491-A2 FILM FORMER IN HAIR DYES Henkel AG & Co. KGaA (DE) 2012-03-07 EP disclosed
WO-2010124897-A2 FILM FORMER IN HAIR DYES HENKEL AG & CO. KGAA (DE) 2010-11-04 WO disclosed
US-4000218-A PROCESS FOR PREPARING PARTICULATE POLYURETHANE POLYMERS AND THE POLYMERS DERIVED THEREFROM UNION CARBIDE CORPORATION (US) 1976-12-28 US disclosed