Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | PPIA | P62937 | 2/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10905610 | 0.89 | BRD4 (0.40) | BRD4MEN1KMT2ASMN1; SMN2SGMS2 | |
| SCHEMBL10729709 | 0.87 | BRD4 (0.42) | BRD4MEN1KMT2ASMN1; SMN2SGMS2 | |
| SCHEMBL10906934 | 0.86 | SMN1; SMN2 (0.42) | BRD4MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL10903906 | 0.86 | BRD4 (0.44) | BRD4MEN1KMT2ASMN1; SMN2SGMS2 | |
| SCHEMBL10903888 | 0.85 | BRD4 (0.43) | BRD4MEN1KMT2ASGMS2PPIA | |
| SCHEMBL10939273 | 0.84 | CYP3A4 (0.36) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL10906389 | 0.83 | CACNA1C (0.44) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL10906999 | 0.81 | BRD4 (0.45) | BRD4MEN1KMT2ASMN1; SMN2SGMS2 | |
| SCHEMBL10906460 | 0.80 | ATM (0.35) | MEN1KMT2A | |
| SCHEMBL10905670 | 0.80 | MAPT (0.44) | BRD4MEN1KMT2ASMN1; SMN2SGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4564640-A | Amidinoureas substituted in both the urea and amidino nitrogen positions | WILLIAM H. RORER, INC. (US) | 1986-01-14 | — | — | US | disclosed |