Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10903309 | 0.88 | TSHR (0.58) | TSHRTDP1PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL10909893 | 0.86 | TSHR (0.61) | TSHRTDP1PKMSMN1; SMN2ALDH1A1 | |
| Ethylenediamine SCHEMBL7747400 | 0.83 | TSHR (0.55) | TSHRTDP1PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL3430112 | 0.83 | TSHR (0.55) | TSHRTDP1PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL56403 | 0.82 | TSHR (0.63) | TSHRTDP1PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL10749240 | 0.81 | TSHR (0.53) | TSHRTDP1PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL14212039 | 0.80 | TSHR (0.57) | TSHRTDP1PKMSMN1; SMN2ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL29207431 | 0.80 | TSHR (0.61) | TSHRTDP1PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL28545578 | 0.80 | TSHR (0.61) | TSHRTDP1PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL9062792 | 0.79 | TSHR (0.56) | TSHRTDP1PKMSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0100900-B1 | NOVEL (3.2.0.) BICYCLOHEPTANONE OXIME ETHERS WITH VALUABLE THERAPEUTIC PROPERTIES | SYNTEX (U.S.A.) INC. (US) | 1986-02-05 | — | — | EP | disclosed |
| US-4552898-A | CARDIOVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-11-12 | — | — | US | disclosed |
| EP-0100900-A1 | Novel (3.2.0.) bicycloheptanone oxime ethers with valuable therapeutic properties | SYNTEX (U.S.A.) INC. (US) | 1984-02-22 | — | — | EP | disclosed |
| US-4423068-A | (3.2.0) Bicycloheptanone oxime ethers with therapeutic properties | SYNTEX (U.S.A.) INC. (US) | 1983-12-27 | — | — | US | disclosed |