Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.40 |
| ▸ | SELE | P16581 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | GRK6 | P43250 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5038235 | 0.89 | — | — | |
| SCHEMBL10906449 | 0.84 | ADORA2A (0.47) | ADORA2AGRK6KDM4EMEN1USP2 | |
| SCHEMBL22415206 | 0.82 | MAPT (0.41) | ADORA2APTPN1HTR2AKDM4EMEN1 | |
| SCHEMBL5039434 | 0.81 | MAPT (0.49) | GRK6KDM4EMEN1USP2MAPT | |
| SCHEMBL17342974 | 0.80 | MAPT (0.43) | ADORA2APTPN1KDM4EMEN1MAPT | |
| SCHEMBL17399120 | 0.80 | ADORA2A (0.45) | ADORA2AKDM4EMEN1USP2MAPT | |
| SCHEMBL10906307 | 0.80 | ADORA2A (0.52) | ADORA2AGRK6KDM4EMEN1USP2 | |
| SCHEMBL10817109 | 0.79 | ADORA2A (0.55) | ADORA2AGRK6KDM4EMEN1USP2 | |
| SCHEMBL92415 | 0.79 | ADORA2A (0.66) | ADORA2AGRK6KDM4EMEN1USP2 | |
| SCHEMBL8508544 | 0.79 | ELANE (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4622169-A | ANTHRAQUINONE OR NAPHTHAQUINONE SUBSTITUTED WITH AMINO GROUP REACTED WITH METAL SALT | THE DOW CHEMICAL COMPANY (US) | 1986-11-11 | — | — | US | disclosed |