Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | RECQL | P46063 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | TIMP3 | P35625 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.47 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.47 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11344916 | 0.93 | APEX1 (0.62) | APEX1KMT2ARECQLHSD17B10TDP1 | |
| SCHEMBL10907842 | 0.91 | APEX1 (0.62) | APEX1KMT2ARECQLHSD17B10TDP1 | |
| SCHEMBL10908350 | 0.90 | APEX1 (0.63) | APEX1KMT2ARECQLHSD17B10TDP1 | |
| SCHEMBL13619183 | 0.87 | APEX1 (0.81) | APEX1KMT2ARECQLHSD17B10TDP1 | |
| SCHEMBL10904451 | 0.86 | APEX1 (0.79) | APEX1KMT2ARECQLHSD17B10TDP1 | |
| SCHEMBL11440872 | 0.85 | APEX1 (0.63) | APEX1KMT2ARECQLHSD17B10TDP1 | |
| SCHEMBL11590673 | 0.85 | APEX1 (0.74) | APEX1KMT2ARECQLHSD17B10TDP1 | |
| SCHEMBL11689238 | 0.85 | APEX1 (0.74) | APEX1KMT2ARECQLHSD17B10TDP1 | |
| SCHEMBL11590648 | 0.84 | APEX1 (0.72) | APEX1KMT2ARECQLHSD17B10TDP1 | |
| SCHEMBL14107314 | 0.84 | APEX1 (0.72) | APEX1KMT2ARECQLHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |