SCHEMBL10909445

SCHEMBL10909445

CC(=O)c1cc(O)cc2ccccc12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 2/20 0.60
NQO2 P16083 1/20 0.53
MAPT P10636 4/20 0.50
KDM4E B2RXH2 4/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
POLB P06746 2/20 0.50
NSD2 O96028 1/20 0.50
MCL1 Q07820 1/20 0.50
ALDH1A1 P00352 4/20 0.49
HPGD P15428 4/20 0.49
MPI P34949 1/20 0.47
MAOB P27338 2/20 0.44
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
DEGS1 O15121 1/20 0.44
CA5A P35218 1/20 0.43
CREBBP Q92793 1/20 0.42
CYP1A2 P05177 2/20 0.42
NR4A1 P22736 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3914053 0.85 CDC25B (0.60) CDC25BNQO2MAPTKDM4EMEN1
SCHEMBL80302 0.82 CDC25B (0.77) CDC25BNQO2MAPTKDM4EMEN1
SCHEMBL30182714 0.82 CDC25B (0.77) CDC25BNQO2MAPTKDM4EMEN1
SCHEMBL6362640 0.81 CYP1A2 (0.53) CDC25BMAPTKDM4EMEN1KMT2A
SCHEMBL25986589 0.81 MAPT (0.62) MAPTKDM4EMEN1KMT2APOLB
SCHEMBL8797558 0.81 CDC25B (0.60) CDC25BNQO2MAPTKDM4EMEN1
SCHEMBL38665356 0.81 MAPT (0.62) MAPTKDM4EMEN1KMT2APOLB
Hydrochloric Acid SCHEMBL3914059 0.81 CDC25B (0.75) CDC25BNQO2MAPTKDM4EMEN1
SCHEMBL1506772 0.81 NQO2 (0.53) CDC25BNQO2MAPTKDM4EMEN1
Ammonia Solution, Strong SCHEMBL9297218 0.81 CDC25B (0.75) CDC25BNQO2MAPTKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4448869-A HYDROXY AND CARBOXY OR ACYL SUBSTITUTED BENZENE OR NAPHTHALENE FUJI PHOTO FILM CO., LTD. (JP) 1984-05-15 US claimed
WO-2022247770-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 上海璎黎药业有限公司 2022-12-01 WO disclosed
EP-1836201-B2 PYRROLIDINE INHIBITORS OF IAP GENENTECH INC (US) 2013-09-04 EP disclosed
US-4617382-A PRINTING; DYEING; SILK, LEATHER, WOOL AND POLYAMIDES CIBA-GEIGY CORPORATION (US) 1986-10-14 US disclosed
US-4448869-A HYDROXY AND CARBOXY OR ACYL SUBSTITUTED BENZENE OR NAPHTHALENE FUJI PHOTO FILM CO., LTD. (JP) 1984-05-15 US disclosed
US-4331596-A Arylazoarylazo-substituted azo, azomethine 1:2 chromium complex dyes CIBA-GEIGY CORPORATION (US) 1982-05-25 US disclosed
US-4116952-A POLYAMIDES CIBA-GEIGY CORPORATION (US) 1978-09-26 US disclosed
US-RE29585-E DYEING WOOL CIBA-GEIGY CORPORATION (US) 1978-03-21 US disclosed
US-4033942-A Chromium complex dye, including azo and azo methine dye compounds CIBA-GEIGY AG (CH) 1977-07-05 US disclosed
US-3978037-A POLYAMIDES CIBA-GEIGY CORPORATION (US) 1976-08-31 US disclosed
US-3971738-A Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component CIBA-GEIGY AG (CH) 1976-07-27 US disclosed
US-3933785-A Azo compounds CIBA-GEIGY AG (CH) 1976-01-20 US disclosed