Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 10/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.43 |
| ▸ | BID | P55957 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560072 | 0.77 | CYSLTR2 (0.52) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9428159 | 0.75 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1LTB4RBIDBCL2L1 | |
| SCHEMBL9560211 | 0.74 | CYSLTR2 (0.51) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9559793 | 0.73 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9428460 | 0.73 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9560053 | 0.72 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1LTB4RBIDBCL2L1 | |
| SCHEMBL9430238 | 0.71 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1LTB4RBIDBCL2L1 | |
| SCHEMBL9856171 | 0.70 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 | |
| SCHEMBL9430233 | 0.70 | BID (0.44) | CYSLTR2CYSLTR1LTB4RBIDBCL2L1 | |
| SCHEMBL9560067 | 0.70 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1BIDBCL2L1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0202759-A2 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1986-11-26 | — | — | EP | disclosed |