Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10909758 | 0.97 | MAPT (0.44) | KMT2APOLBMAPTCHRNA7KDM4E | |
| SCHEMBL10911955 | 0.93 | MAPT (0.52) | KMT2APOLBMAPTCHRNA7 | |
| SCHEMBL10912912 | 0.93 | KMT2A (0.45) | KMT2APOLBMAPTCHRNA7 | |
| SCHEMBL10912142 | 0.92 | MAPT (0.51) | KMT2AMAPTCHRNA7 | |
| SCHEMBL10909891 | 0.92 | MAPT (0.51) | KMT2AMAPTCHRNA7 | |
| SCHEMBL10912820 | 0.91 | MAPT (0.46) | KMT2APOLBMAPTCHRNA7 | |
| SCHEMBL10911744 | 0.90 | MAPT (0.53) | KMT2APOLBMAPTCHRNA7HTT | |
| SCHEMBL10911656 | 0.89 | POLB (0.45) | KMT2APOLBMAPTKDM4EALDH1A1 | |
| SCHEMBL10912387 | 0.88 | POLB (0.41) | KMT2APOLBKDM4EALDH1A1MAPK1 | |
| SCHEMBL10911933 | 0.88 | MAPT (0.46) | KMT2APOLBMAPTCHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |