Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.55 |
| ▸ | PGR | P06401 | 3/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | APEX1 | P27695 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.42 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10912102 | 1.00 | NR1I2 (0.55) | NR1I2PGRPTGS2TDP1MAPT | |
| SCHEMBL10909840 | 0.96 | NR1I2 (0.54) | NR1I2PGRPTGS2TDP1MAPT | |
| SCHEMBL10914384 | 0.96 | NR1I2 (0.54) | NR1I2PGRPTGS2TDP1MAPT | |
| SCHEMBL10420013 | 0.90 | NR1I2 (0.59) | NR1I2PGRPTGS2TDP1MAPT | |
| SCHEMBL10420015 | 0.90 | NR1I2 (0.59) | NR1I2PGRPTGS2TDP1MAPT | |
| SCHEMBL10912081 | 0.89 | NR1I2 (0.52) | NR1I2PGRPTGS2TDP1MAPT | |
| SCHEMBL10912077 | 0.89 | NR1I2 (0.52) | NR1I2PGRPTGS2TDP1MAPT | |
| SCHEMBL10739955 | 0.87 | TDP1 (0.49) | NR1I2PGRTDP1MAPTAPEX1 | |
| SCHEMBL10739962 | 0.87 | TDP1 (0.49) | NR1I2PGRTDP1MAPTAPEX1 | |
| SCHEMBL10912586 | 0.87 | TDP1 (0.48) | NR1I2PGRTDP1MAPTAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4598147-A | THIAZOLE INTERMEDIATES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-01 | — | — | US | disclosed |
| EP-0007633-B1 | CEPHEM COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-04-18 | — | — | EP | disclosed |
| US-4372952-A | Cephem compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-02-08 | — | — | US | disclosed |
| EP-0049539-A1 | Thiazole derivatives for preparing cephem compounds and processes for their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-04-14 | — | — | EP | disclosed |
| US-4284631-A | 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-08-18 | — | — | US | disclosed |
| EP-0007633-A2 | Cephem compounds, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-06 | — | — | EP | disclosed |