SCHEMBL1091

SCHEMBL1091

[c]1ccc2ccccc2c1

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 7/20 0.47
ALOX12 P18054 1/20 0.47
CYP1A2 P05177 4/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
ALDH1A1 P00352 2/20 0.32
HSD17B10 Q99714 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
TSHR P16473 1/20 0.32
CYP3A4 P08684 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14796756 1.00 CYP2A6 (0.47) CYP2A6ALOX12CYP1A2CA1CA2
Water SCHEMBL27894314 1.00 CYP2A6 (0.47) CYP2A6ALOX12CYP1A2CA1CA2
Hydroxyl Radical SCHEMBL28175225 0.97 CYP2A6 (0.44) CYP2A6ALOX12CYP1A2CA1CA2
SCHEMBL27432717 0.97 CYP2A6 (0.44) CYP2A6ALOX12CYP1A2CA1CA2
SCHEMBL26087222 0.97 CYP2A6 (0.44) CYP2A6ALOX12CYP1A2CA1CA2
SCHEMBL8588369 0.97 CYP2A6 (0.44) CYP2A6ALOX12CYP1A2CA1CA2
SCHEMBL27684039 0.97 CYP2A6 (0.44) CYP2A6ALOX12CYP1A2CA1CA2
SCHEMBL28397979 0.97 CYP2A6 (0.44) CYP2A6ALOX12CYP1A2CA1CA2
SCHEMBL11505201 0.97 CYP2A6 (0.44) CYP2A6ALOX12CYP1A2CA1CA2
Water SCHEMBL27744164 0.97 CYP2A6 (0.44) CYP2A6ALOX12CYP1A2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 122827 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6372780-B1 None US claimed
US-6410577-B1 None US claimed
JP-5155847-A None JP claimed
US-20240239821-A1 N-ACYL FOSMIDOMYCIN PRODRUG ANALOGS AS NOVEL ANTIINFECTIVE AGENTS THE GEORGE WASHINGTON UNIVERSITY 2024-07-18 US claimed
CN-118344336-A 2-Alkylene-5-aminothiophene-3-ketone compound and preparation method and application thereof 浙江师范大学 2024-07-16 CN claimed
CN-118344293-A Acenaphthene dimer derivative, and preparation method and application thereof 中国石油化工股份有限公司 2024-07-16 CN claimed
CN-118344303-A Benzo [ c ] [1,5] oxazacine compound and synthesis method thereof 江苏师范大学 2024-07-16 CN claimed
CN-118344291-A Method for preparing imide by rearrangement of isoamide and application thereof 中国石油化工股份有限公司 2024-07-16 CN claimed
CN-118344292-A Acenaphthene derivative and preparation method thereof, acenaphthene derivative material and preparation method and application thereof 中国石油化工股份有限公司 2024-07-16 CN claimed
US-12041848-B2 Heterocyclic compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2024-07-16 US claimed
US-3946030-A FROM ARYL AMINES, SULFUR, UREA, THIOUREA, CYANAMIDE PHILLIPS PETROLEUM COMPANY (US) 1976-03-23 US claimed
US-3943154-A PLANT AND ANIMAL GROWTH REGULATORS SANITIZED INCORPORATED (US) 1976-03-09 US claimed
US-3940449-A SOLVENTS, DIELECTRIC FLUIDS THE DOW CHEMICAL COMPANY (US) 1976-02-24 US claimed
US-3939184-A Production of carbonyl compounds substituted in α-position BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1976-02-17 US claimed
US-3933715-A N-substituted maleic imide preservative for aqueous dispersions of polymers derived from α, β-ethylenically unsaturated monomers HOECHST AKTIENGESELLSCHAFT (DT) 1976-01-20 US claimed
US-3932355-A POLYMERIZATION IN THE PRESENCE OF A POLYETHER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-01-13 US claimed
US-3932452-A 1-Arylmethyl-2-imidazolidinones MORTON-NORWICH PRODUCTS, INC. (US) 1976-01-13 US claimed
US-3932389-A ANTIULCER AGENTS PFIZER INC. (US) 1976-01-13 US claimed
US-3932301-A NYLON, POLYESTERS STERLING DRUG INC. (US) 1976-01-13 US claimed
US-3931355-A SILYL ETHER OF A TETRAARYL 1,2 GLYCOL CATALYST BAYER AKTIENGESELLSCHAFT (DT) 1976-01-06 US claimed