Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | ACR | P10323 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10910653 | 1.00 | CYP2C9 (0.56) | CYP2C9MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL11406369 | 0.96 | CYP2C9 (0.60) | CYP2C9MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL11411864 | 0.96 | CYP2C9 (0.60) | CYP2C9MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL10910678 | 0.93 | CYP2C9 (0.54) | CYP2C9MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL10910666 | 0.93 | CYP2C9 (0.54) | CYP2C9MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL10907931 | 0.93 | CYP2C9 (0.54) | CYP2C9MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL10907936 | 0.93 | CYP2C9 (0.54) | CYP2C9MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL10910674 | 0.93 | CYP2C9 (0.54) | CYP2C9MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL10938649 | 0.92 | CYP2C9 (0.66) | CYP2C9MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL10898816 | 0.92 | CYP2C9 (0.66) | CYP2C9MAPTALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4620938-A | Hydroterphenyls | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-11-04 | — | — | US | disclosed |
| EP-0094487-A1 | Hydroterphenyls, their preparation and their use in dielectric liquid crystal material | MERCK PATENT GmbH (DE) | 1983-11-23 | — | — | EP | disclosed |