Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10912198 | 0.94 | KCNH2 (0.41) | POLBALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL10914345 | 0.88 | POLB (0.44) | POLBALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL10911744 | 0.87 | MAPT (0.53) | POLBKMT2AHTTMAPTCHRNA7 | |
| SCHEMBL10913841 | 0.85 | POLB (0.39) | POLBALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL10913282 | 0.85 | MAPT (0.47) | POLBKDM4EKMT2AMAPTCHRNA7 | |
| SCHEMBL10912048 | 0.85 | POLB (0.46) | POLBALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL10909758 | 0.84 | MAPT (0.44) | POLBALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL10911955 | 0.84 | MAPT (0.52) | POLBKMT2AMAPTCHRNA7 | |
| SCHEMBL10911933 | 0.83 | MAPT (0.46) | POLBKMT2AMAPTCHRNA7 | |
| SCHEMBL10912142 | 0.83 | MAPT (0.51) | KMT2AMAPTCHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |