Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 9/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | TDP2 | O95551 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10916084 | 1.00 | MALT1 (0.55) | MALT1CYP1A2CYP2C19CYP3A4MAPT | |
| SCHEMBL10914362 | 0.85 | MALT1 (0.55) | MALT1CYP1A2CYP2C19CYP3A4MAPT | |
| SCHEMBL10914365 | 0.85 | MALT1 (0.55) | MALT1CYP1A2CYP2C19CYP3A4MAPT | |
| SCHEMBL10049524 | 0.85 | MALT1 (0.62) | MALT1CYP1A2CYP2C19CYP3A4MAPT | |
| Hydrochloric Acid SCHEMBL10951308 | 0.84 | MALT1 (0.54) | MALT1CYP1A2CYP2C19CYP3A4MAPT | |
| SCHEMBL10915342 | 0.84 | MALT1 (0.61) | MALT1CYP1A2CYP2C19CYP3A4MAPT | |
| SCHEMBL10915343 | 0.84 | MALT1 (0.61) | MALT1CYP1A2CYP2C19CYP3A4MAPT | |
| SCHEMBL10916618 | 0.83 | MALT1 (0.52) | MALT1CYP1A2CYP2C19CYP3A4MAPT | |
| SCHEMBL10916047 | 0.81 | MALT1 (0.60) | MALT1CYP1A2CYP2C19CYP3A4MAPT | |
| SCHEMBL10916049 | 0.81 | MALT1 (0.60) | MALT1CYP1A2CYP2C19CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0183649-A1 | Nitrogen derivatives from oxo compounds | CIBA-GEIGY AG (CH) | 1986-06-04 | — | — | EP | claimed |