Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | PPARD | Q03181 | 7/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1415103 | 0.98 | KMT2A (0.56) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL1415374 | 0.93 | — | — | |
| SCHEMBL3987605 | 0.81 | KMT2A (0.52) | KMT2AMAPTCES2CES1AKR1B1 | |
| SCHEMBL13093671 | 0.80 | MAPT (0.57) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL11484526 | 0.80 | MAPT (0.57) | KMT2AMAPTCES2CES1HAO1 | |
| Ethyne SCHEMBL3249356 | 0.79 | KMT2A (0.68) | KMT2AMAPTCES2CES1AKR1B1 | |
| SCHEMBL3987265 | 0.79 | KMT2A (0.56) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL379850 | 0.79 | KMT2A (0.56) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL3987319 | 0.79 | KMT2A (0.56) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL1668639 | 0.79 | KMT2A (0.56) | KMT2AMAPTCES2CES1HAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0061197-B1 | ALPHA CHAIN DIENIC PROSTANOIC ACID DERIVATIVES | G.D. Searle & Co. (US) | 1986-05-21 | — | — | EP | disclosed |
| EP-0061197-A1 | Alpha chain dienic prostanoic acid derivatives | G.D. Searle & Co. (US) | 1982-09-29 | — | — | EP | disclosed |
| US-4312994-A | α Chain dienic prostanoic acid derivatives | G. D. SEARLE & CO. (US) | 1982-01-26 | — | — | US | disclosed |