Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | MPL | P40238 | 2/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10921540 | 0.92 | RARB (0.64) | RARBMAOBMAOAKMT2AMPL | |
| SCHEMBL10919580 | 0.90 | RARB (0.70) | RARBKMT2AMPL | |
| SCHEMBL10922495 | 0.89 | RARB (0.73) | RARBKMT2A | |
| SCHEMBL10918630 | 0.89 | RARB (0.73) | RARBKMT2A | |
| SCHEMBL10920791 | 0.89 | RARB (0.73) | RARBKMT2A | |
| SCHEMBL10919359 | 0.89 | RARB (0.73) | RARBKMT2A | |
| SCHEMBL10922911 | 0.89 | RARB (0.73) | RARBKMT2A | |
| SCHEMBL15797758 | 0.88 | RARB (0.67) | RARBKMT2AMPLNPC1RAB9A | |
| SCHEMBL10922772 | 0.88 | RARB (0.52) | RARBMAOBMAOAHSD17B1KMT2A | |
| SCHEMBL10924018 | 0.87 | RARB (0.55) | RARBMPLPLK1NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0088907-B1 | HALOGEN BIPHENYL DERIVATIVES | MERCK PATENT GmbH (DE) | 1985-10-16 | — | — | EP | disclosed |
| US-4544771-A | LIQUID CRYSTAL DIELECTRICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-10-01 | — | — | US | disclosed |
| US-4505838-A | Halogenobiphenyl derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-03-19 | — | — | US | disclosed |
| EP-0088907-A1 | Halogen biphenyl derivatives | MERCK PATENT GmbH (DE) | 1983-09-21 | — | — | EP | disclosed |