Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.80 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | KDM1A | O60341 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | RORC | P51449 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | CFTR | P13569 | 2/20 | 0.56 |
| ▸ | MPL | P40238 | 1/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.56 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MRE11 | P49959 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10815310 | 0.91 | ABL1 (0.80) | ABL1GSTO1MAPTMEN1KMT2A | |
| SCHEMBL18387706 | 0.89 | ABL1 (1.00) | ABL1GSTO1MAPTMEN1KMT2A | |
| SCHEMBL29419362 | 0.89 | ABL1 (1.00) | ABL1GSTO1MAPTMEN1KMT2A | |
| SCHEMBL2753902 | 0.85 | ABL1 (0.71) | ABL1GSTO1MAPTMEN1KMT2A | |
| SCHEMBL3606891 | 0.83 | ABL1 (0.68) | ABL1GSTO1MAPTMEN1KMT2A | |
| SCHEMBL8684727 | 0.83 | ABL1 (0.68) | ABL1GSTO1MAPTMEN1KMT2A | |
| SCHEMBL10923160 | 0.83 | ABL1 (0.61) | ABL1GSTO1MAPTMEN1KMT2A | |
| SCHEMBL10926224 | 0.83 | MEN1 (0.71) | ABL1GSTO1MAPTMEN1KMT2A | |
| SCHEMBL21484726 | 0.82 | ABL1 (0.73) | ABL1GSTO1MAPTMEN1KMT2A | |
| SCHEMBL10924496 | 0.82 | ABL1 (0.78) | ABL1GSTO1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0069154-B1 | NOVEL THIAZOLE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND MEDICINAL COMPOSITION CONTAINING SAME | MITSUI TOATSU KAGAKU KABUSHIKI KAISHA (JP) | 1986-10-15 | — | — | EP | disclosed |
| US-4501750-A | ANTIARTHRITIC AGENTS | Mitsui Toatsu Kaguku Kabushiki Kaisha (JP) | 1985-02-26 | — | — | US | disclosed |
| EP-0069154-A1 | NOVEL THIAZOLE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND MEDICINAL COMPOSITION CONTAINING SAME | MITSUI TOATSU KAGAKU KABUSHIKI KAISHA (JP) | 1983-01-12 | — | — | EP | disclosed |