SCHEMBL109256

SCHEMBL109256

CCCCCc1ccc(N)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.72
MAOB P27338 2/20 0.64
ALDH1A1 P00352 3/20 0.59
KDM4E B2RXH2 3/20 0.59
ESR1 P03372 2/20 0.59
ADRA2A P08913 2/20 0.59
ADORA3 P0DMS8 2/20 0.59
TACR2 P21452 2/20 0.59
SLC6A2 P23975 2/20 0.59
SLC6A4 P31645 2/20 0.59
SLC6A3 Q01959 2/20 0.59
HSD17B10 Q99714 2/20 0.59
LMNA P02545 1/20 0.59
SHBG P04278 1/20 0.59
TP53 P04637 1/20 0.59
CYP3A4 P08684 1/20 0.59
HSPD1 P10809 1/20 0.59
ADRB3 P13945 1/20 0.59
HTR2C P28335 1/20 0.59
HSPE1 P61604 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22346225 0.98 HTR2A (0.76) HTR2AMAOBALDH1A1KDM4EESR1
Tridecane SCHEMBL22346186 0.98 HTR2A (0.76) HTR2AMAOBALDH1A1KDM4EESR1
SCHEMBL22346499 0.98 HTR2A (0.76) HTR2AMAOBALDH1A1KDM4EESR1
SCHEMBL23754735 0.98 HTR2A (0.76) HTR2AMAOBALDH1A1KDM4EESR1
SCHEMBL22346250 0.98 HTR2A (0.76) HTR2AMAOBALDH1A1KDM4EESR1
SCHEMBL25171839 0.98 HTR2A (0.76) HTR2AMAOBALDH1A1KDM4EESR1
Pentadecane SCHEMBL22346204 0.98 HTR2A (0.76) HTR2AMAOBALDH1A1KDM4EESR1
SCHEMBL23754742 0.98 HTR2A (0.76) HTR2AMAOBALDH1A1KDM4EESR1
SCHEMBL22346194 0.98 HTR2A (0.76) HTR2AMAOBALDH1A1KDM4EESR1
SCHEMBL22346501 0.98 HTR2A (0.76) HTR2AMAOBALDH1A1KDM4EESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 670 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228819-A1 WATER-BORNE COATING COMPOSITION, ITS PREPARATION METHOD AND APPLICATION THEREOF BASF COATINGS GMBH (DE) 2024-07-11 US claimed
CN-117916657-A Liquid crystal aligning agent, liquid crystal alignment film, method for manufacturing liquid crystal display element, and liquid crystal display element 日产化学株式会社 2024-04-19 CN claimed
CN-115724764-A Preparation method of azobenzene light-operated high-molecular phase change energy storage material at ultralow temperature 天津大学 2023-03-03 CN claimed
CN-115611821-A Low dielectric and high heat-resistant azacalixarene resin and preparation method and application thereof 山东大学 2023-01-17 CN claimed
WO-2022258507-A1 WATER-BORNE COATING COMPOSITION, ITS PREPARATION METHOD AND APPLICATION THEREOF BASF COATINGS GMBH (DE) 2022-12-15 WO claimed
CN-112946089-A Method for determining content and/or molecular structure of nitride in diesel oil 中国石油化工股份有限公司 2021-06-11 CN claimed
CN-109879805-A A Pa replaces the preparation method of Buddhist nun 苏州富士莱医药股份有限公司 2019-06-14 CN claimed
US-20170305859-A1 An Anticonvulsant Compound ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE (GB) 2017-10-26 US claimed
EP-3191088-A1 AN ANTICONVULSANT COMPOUND Royal Holloway And Bedford New College (GB) 2017-07-19 EP claimed
WO-2016038379-A1 AN ANTICONVULSANT COMPOUND ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE (GB) 2016-03-17 WO claimed
US-20010016608-A1 Attaching an aliphatic carbon chain that may contain aromatic residues to carbon nanotubes, and dissolving in an organic solvent CARBON SOLUTIONS, INC. 2001-08-23 US claimed
US-6187823-B1 CARBOXYLATION; POLISHING; AMIDATION; DISSOLVING UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2001-02-13 US claimed
WO-2000050406-A1 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES LION BIOSCIENCE AG (DE) 2000-08-31 WO claimed
EP-0863877-A4 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES TORREY PINES INST (US) 1999-07-21 EP claimed
US-5874443-A BIOSYNTHESIS TREGA BIOSCIENCES, INC. (US) 1999-02-23 US claimed
EP-0863877-A1 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) 1998-09-16 EP claimed
WO-1997016428-A1 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) 1997-05-09 WO claimed
US-4911907-A Aromatic alcohol or amine TAISHO PHARMACEUTICAL CO., LTD. (JP) 1990-03-27 US claimed
US-4350674-A VISUALIZING HEPTOBILIARY SYSTEM HOECHST AKTIENGESELLSCHAFT (DE) 1982-09-21 US claimed
EP-0019790-A2 Technetium-99m labeled acetanilidoiminodiacetates for liver function diagnosis and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1980-12-10 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170305859-A1 An Anticonvulsant Compound PSEN2, BACE2, APP HTR2A 551/4885MAOB 7/4885ALDH1A1 790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.