Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 10/20 | 0.53 |
| ▸ | PTGER4 | P35408 | 10/20 | 0.53 |
| ▸ | PTGER3 | P43115 | 9/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | PTGFR | P43088 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10930858 | 0.97 | PTGER4 (0.58) | PTGER2PTGER4PTGER3FFAR4FFAR1 | |
| SCHEMBL10930068 | 0.97 | PTGER4 (0.58) | PTGER2PTGER4PTGER3FFAR4FFAR1 | |
| SCHEMBL10929043 | 0.94 | PTGER4 (0.49) | PTGER2PTGER4PTGER3FFAR4FFAR1 | |
| SCHEMBL10929058 | 0.84 | PTGER3 (0.46) | PTGER2PTGER4PTGER3TBXA2RPTGFR | |
| SCHEMBL10928581 | 0.81 | S1PR1 (0.44) | PTGER2PTGER4PTGER3TBXA2RPTGFR | |
| SCHEMBL10927713 | 0.81 | PTGFR (0.42) | PTGER2PTGER4PTGER3PTGFRPTGER1 | |
| SCHEMBL10928527 | 0.80 | PTGER3 (0.44) | PTGER2PTGER4PTGER3TBXA2RPTGFR | |
| SCHEMBL10927681 | 0.80 | PTGFR (0.43) | PTGER2PTGER4PTGER3TBXA2RPTGFR | |
| SCHEMBL10932230 | 0.80 | TSHR (0.65) | PTGER2PTGER4PTGER3TSHRHIF1A | |
| SCHEMBL10931884 | 0.79 | PTGFR (0.42) | PTGER2PTGER4PTGER3PTGFRPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0139265-A2 | Imidazolidine prostaglandins | SYNTEX (U.S.A.) INC. (US) | 1985-05-02 | — | — | EP | disclosed |