Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 11/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10930750 | 0.99 | RARB (0.46) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL10928793 | 0.96 | RARB (0.49) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL10930497 | 0.95 | RARB (0.50) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL10933631 | 0.95 | RARB (0.50) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL10928614 | 0.95 | RARB (0.50) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL10931237 | 0.95 | RARB (0.47) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL10930048 | 0.94 | RARB (0.48) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL10928483 | 0.94 | RARB (0.48) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL10930250 | 0.94 | RARB (0.48) | RARBMEN1ALDH1A1RARAMAPT | |
| SCHEMBL10927208 | 0.92 | ESR2 (0.46) | RARBMEN1ALDH1A1RARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4505837-A | Liquid crystalline phenylcyclohexene derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-03-19 | — | — | US | disclosed |