Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 6/20 | 0.67 |
| ▸ | RARB | P10826 | 5/20 | 0.67 |
| ▸ | RARA | P10276 | 4/20 | 0.48 |
| ▸ | TTR | P02766 | 2/20 | 0.45 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.40 |
| ▸ | CHRNG | P07510 | 1/20 | 0.40 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | CHRND | Q07001 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10935912 | 0.83 | RARG (0.64) | RARGRARBRARASRD5A2ALDH1A1 | |
| SCHEMBL10935919 | 0.83 | RARG (0.64) | RARGRARBRARASRD5A2ALDH1A1 | |
| SCHEMBL1782039 | 0.82 | RARG (0.66) | RARGRARBALDH1A1CHRNA1CHRNG | |
| SCHEMBL1422581 | 0.82 | RARG (0.66) | RARGRARBALDH1A1CHRNA1CHRNG | |
| SCHEMBL1782019 | 0.82 | RARG (0.66) | RARGRARBALDH1A1CHRNA1CHRNG | |
| SCHEMBL10933004 | 0.80 | RARG (1.00) | RARGRARBRARAALDH1A1CHRNA1 | |
| SCHEMBL10934599 | 0.80 | RARG (1.00) | RARGRARBRARAALDH1A1CHRNA1 | |
| SCHEMBL10935866 | 0.80 | RARG (0.48) | RARGRARBALDH1A1PTPN1NPC1 | |
| SCHEMBL10938633 | 0.78 | RARG (0.46) | RARGRARBRARATTRCHRNA1 | |
| SCHEMBL10933048 | 0.78 | RARG (0.46) | RARGRARBRARATTRCHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155940-A1 | BENZONORBORNENYL, BENZOPYRANYL AND BENZOTHIOPYRANYL RETINOIC ACID ANALOGUES | SRI INTERNATIONAL (US) | 1985-10-02 | — | — | EP | disclosed |
| WO-1985000806-A1 | BENZONORBORNENYL, BENZOPYRANYL AND BENZOTHIOPYRANYL RETINOIC ACID ANALOGUES | SRI INTERNATIONAL (US) | 1985-02-28 | — | — | WO | disclosed |