Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23201809 | 0.97 | GAA (0.58) | GAAPOLBGFERATML3MBTL1 | |
| SCHEMBL10935494 | 0.97 | GAA (0.58) | GAAPOLBGFERATML3MBTL1 | |
| SCHEMBL29069391 | 0.96 | GAA (0.57) | GAAPOLBGFERATML3MBTL1 | |
| SCHEMBL29069392 | 0.96 | GAA (0.57) | GAAPOLBGFERATML3MBTL1 | |
| SCHEMBL10481422 | 0.94 | GAA (0.61) | GAAPOLBGFERATML3MBTL1 | |
| SCHEMBL23201807 | 0.94 | GAA (0.61) | GAAPOLBGFERATML3MBTL1 | |
| SCHEMBL10933319 | 0.85 | MME (0.54) | POLBALDH1A1HSD17B10LMNA | |
| SCHEMBL7258036 | 0.85 | MME (0.54) | POLBALDH1A1HSD17B10LMNA | |
| SCHEMBL12678083 | 0.82 | MME (0.54) | POLBALDH1A1HSD17B10KDM4ELMNA | |
| SCHEMBL7257313 | 0.82 | MME (0.54) | POLBALDH1A1HSD17B10KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135429-A1 | The synthesis of cyclopropane amino acids and peptides | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1985-03-27 | — | — | EP | disclosed |
| WO-1985000809-A1 | THE SYNTHESIS OF CYCLOPROPANE AMINO ACIDS AND PEPTIDES | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1985-02-28 | — | — | WO | disclosed |