Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.75 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.61 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.61 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.61 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.61 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.61 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.61 |
| ▸ | AKT1 | P31749 | 5/20 | 0.56 |
| ▸ | AKT2 | P31751 | 3/20 | 0.56 |
| ▸ | AKT3 | Q9Y243 | 3/20 | 0.56 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.56 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.56 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.56 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.55 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | PRKCG | P05129 | 1/20 | 0.51 |
| ▸ | PRKCB | P05771 | 1/20 | 0.51 |
| ▸ | PRKCA | P17252 | 1/20 | 0.51 |
| ▸ | PRKCH | P24723 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10884407 | 1.00 | PLA2G2C (0.75) | PLA2G2CLPAR1LPAR3LPAR5LPAR6 | |
| SCHEMBL4485528 | 1.00 | PLA2G2C (0.75) | PLA2G2CLPAR1LPAR3LPAR5LPAR6 | |
| SCHEMBL11102642 | 0.91 | LPAR1 (0.68) | PLA2G2CLPAR1LPAR3LPAR5LPAR6 | |
| SCHEMBL29206150 | 0.90 | PLA2G2C (0.73) | PLA2G2CLPAR1LPAR3LPAR5LPAR6 | |
| SCHEMBL931685 | 0.90 | PLA2G2C (0.73) | PLA2G2CLPAR1LPAR3LPAR5LPAR6 | |
| SCHEMBL25394384 | 0.90 | PLA2G2C (0.73) | PLA2G2CLPAR1LPAR3LPAR5LPAR6 | |
| SCHEMBL29206151 | 0.90 | PLA2G2C (0.73) | PLA2G2CLPAR1LPAR3LPAR5LPAR6 | |
| SCHEMBL22092476 | 0.90 | PLA2G2C (0.73) | PLA2G2CLPAR1LPAR3LPAR5LPAR6 | |
| SCHEMBL21568785 | 0.90 | PLA2G2C (0.73) | PLA2G2CLPAR1LPAR3LPAR5LPAR6 | |
| SCHEMBL23300849 | 0.90 | PLA2G2C (0.73) | PLA2G2CLPAR1LPAR3LPAR5LPAR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4544512-A | ANTITUMOR AGENTS, FUNGICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-10-01 | — | — | US | disclosed |
| EP-0050460-B1 | TRIDECYLOXY- OR TETRADECYLOXY-PROPANE DERIVATIVES, AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 1985-07-10 | — | — | EP | disclosed |
| US-4426525-A | ANTITUMOR, ANTIMYCOTIC, ANTIPROTOZOA | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-01-17 | — | — | US | disclosed |
| EP-0050460-A2 | Tridecyloxy- or tetradecyloxy-propane derivatives, and their use | Takeda Chemical Industries, Ltd. (JP) | 1982-04-28 | — | — | EP | disclosed |