Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 9/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | PEPD | P12955 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10935341 | 1.00 | CYP1A2 (0.50) | CYP1A2CYP2C9CYP2C19HTTACE | |
| SCHEMBL10520357 | 0.89 | ACE (0.45) | CYP1A2CYP2C9CYP2C19HTTACE | |
| SCHEMBL10520350 | 0.89 | ACE (0.45) | CYP1A2CYP2C9CYP2C19HTTACE | |
| SCHEMBL10799424 | 0.88 | ACE (0.62) | ACELMNASMN1; SMN2ABCB11MAPT | |
| SCHEMBL10799388 | 0.88 | ACE (0.62) | ACELMNASMN1; SMN2ABCB11MAPT | |
| SCHEMBL10520981 | 0.87 | ACE (0.50) | ACELMNASMN1; SMN2ABCB11FKBP1A | |
| SCHEMBL10520986 | 0.87 | ACE (0.50) | ACELMNASMN1; SMN2ABCB11FKBP1A | |
| SCHEMBL10520254 | 0.84 | ACE (0.45) | CYP1A2CYP2C9CYP2C19HTTACE | |
| SCHEMBL10520260 | 0.84 | ACE (0.45) | CYP1A2CYP2C9CYP2C19HTTACE | |
| SCHEMBL10521977 | 0.84 | ACE (0.44) | CYP1A2CYP2C9CYP2C19HTTACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60185762-A | — | — | None | — | — | JP | disclosed |
| JP-S60185762-A | PROLINE DERIVATIVE | OTSUKA PHARMACEUT FACTORY INC | 1985-09-21 | — | — | JP | disclosed |