Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 6/20 | 0.50 |
| ▸ | RARB | P10826 | 5/20 | 0.50 |
| ▸ | RXRA | P19793 | 6/20 | 0.39 |
| ▸ | RXRB | P28702 | 3/20 | 0.39 |
| ▸ | RXRG | P48443 | 3/20 | 0.39 |
| ▸ | RARA | P10276 | 2/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.32 |
| ▸ | CHRNG | P07510 | 1/20 | 0.32 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10936689 | 1.00 | RARG (0.50) | RARGRARBRXRARXRBRXRG | |
| SCHEMBL10936009 | 0.87 | RARG (0.51) | RARGRARBRXRARXRBRXRG | |
| SCHEMBL10936000 | 0.87 | RARG (0.51) | RARGRARBRXRARXRBRXRG | |
| SCHEMBL10934189 | 0.86 | RARG (0.68) | RARGRARBRXRARARASRD5A2 | |
| SCHEMBL10934181 | 0.86 | RARG (0.68) | RARGRARBRXRARARASRD5A2 | |
| SCHEMBL10934173 | 0.86 | RARG (0.68) | RARGRARBRXRARARASRD5A2 | |
| SCHEMBL10934971 | 0.84 | RARG (0.48) | RARGRARBRXRARXRBRXRG | |
| SCHEMBL10934968 | 0.84 | RARG (0.48) | RARGRARBRXRARXRBRXRG | |
| SCHEMBL10936685 | 0.82 | RARG (0.73) | RARGRARBRXRARXRBRXRG | |
| SCHEMBL10936673 | 0.82 | RARG (0.73) | RARGRARBRXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155940-A1 | BENZONORBORNENYL, BENZOPYRANYL AND BENZOTHIOPYRANYL RETINOIC ACID ANALOGUES | SRI INTERNATIONAL (US) | 1985-10-02 | — | — | EP | disclosed |
| WO-1985000806-A1 | BENZONORBORNENYL, BENZOPYRANYL AND BENZOTHIOPYRANYL RETINOIC ACID ANALOGUES | SRI INTERNATIONAL (US) | 1985-02-28 | — | — | WO | disclosed |