Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.80 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.51 |
| ▸ | ITGAV | P06756 | 3/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 4/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29624416 | 1.00 | SYK (0.80) | SYKATMITGB3ITGAVCTRB1 | |
| SCHEMBL14265354 | 1.00 | SYK (0.80) | SYKATMITGB3ITGAVCTRB1 | |
| SCHEMBL30946052 | 0.91 | SYK (0.77) | SYKATMCTRB1CTSKMAPT | |
| SCHEMBL2627398 | 0.89 | SYK (1.00) | SYKATMCTRB1CTSKMAPT | |
| SCHEMBL6310843 | 0.89 | SYK (0.82) | SYKATMCTRB1CTSKMAPT | |
| SCHEMBL2627375 | 0.89 | SYK (0.82) | SYKATMCTRB1CTSKMAPT | |
| SCHEMBL3271846 | 0.89 | SYK (0.82) | SYKATMCTRB1CTSKMAPT | |
| SCHEMBL6310847 | 0.89 | SYK (0.82) | SYKATMCTRB1CTSKMAPT | |
| SCHEMBL6310853 | 0.89 | SYK (0.82) | SYKATMCTRB1CTSKMAPT | |
| SCHEMBL3582905 | 0.89 | SYK (0.82) | SYKATMCTRB1CTSKMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114917361-A | Antibody Drug Conjugates (ADC) and antibody prodrug conjugates (APDC) with enzyme cleavable groups | 拜耳医药股份有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-107635586-B | Antibody-drug conjugates (ADC) of KSP inhibitors with aglycosylated anti-TWEAKR antibodies | 拜耳医药股份有限公司 | 2021-09-24 | — | — | CN | disclosed |
| CN-106163568-B | Antibody Drug Conjugates (ADC) containing spindle Kinesin (KSP) | 拜耳制药股份公司 | 2021-03-23 | — | — | CN | disclosed |
| US-4521432-A | ANTIDIABEWTIC, REAGENT FOR STUDYING FATTY ACID METABOLISM | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-06-04 | — | — | US | disclosed |
| EP-0080695-B1 | PHYSIOLOGICALLY ACTIVE SUBSTANCE FA-5859, ITS DERIVATIVE; THEIR PRODUCTION AND ANTIDIABETIC AGENTS CONTAINING SAID COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 1985-04-17 | — | — | EP | disclosed |
| EP-0080695-A1 | Physiologically active substance FA-5859, its derivative; their production and antidiabetic agents containing said compounds | Takeda Chemical Industries, Ltd. (JP) | 1983-06-08 | — | — | EP | disclosed |