Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | APEX1 | P27695 | 3/20 | 0.40 |
| ▸ | APAF1 | O14727 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.40 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10937739 | 1.00 | PTGS1 (0.42) | PTGS1ABCB11PDE4DCTDSP1NR1I2 | |
| SCHEMBL10644360 | 0.91 | TDP1 (0.40) | PTGS1ABCB11PDE4DCTDSP1NR1I2 | |
| SCHEMBL10644366 | 0.91 | TDP1 (0.40) | PTGS1ABCB11PDE4DCTDSP1NR1I2 | |
| SCHEMBL10675732 | 0.90 | TDP1 (0.51) | PTGS1ABCB11PDE4DCTDSP1NR1I2 | |
| SCHEMBL10675734 | 0.90 | TDP1 (0.51) | PTGS1ABCB11PDE4DCTDSP1NR1I2 | |
| SCHEMBL10649189 | 0.90 | TDP1 (0.39) | PTGS1ABCB11PDE4DCTDSP1NR1I2 | |
| SCHEMBL9481080 | 0.88 | PTGS1 (0.44) | PTGS1ABCB11PDE4DCTDSP1NR1I2 | |
| SCHEMBL9481088 | 0.88 | PTGS1 (0.44) | PTGS1ABCB11PDE4DCTDSP1NR1I2 | |
| SCHEMBL10935950 | 0.88 | NR1I2 (0.40) | PTGS1ABCB11PDE4DCTDSP1NR1I2 | |
| SCHEMBL10935957 | 0.88 | NR1I2 (0.40) | PTGS1ABCB11PDE4DCTDSP1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499088-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-02-12 | — | — | US | disclosed |