Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 2/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CFB | P00751 | 2/20 | 0.37 |
| ▸ | TPMT | P51580 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10933546 | 0.76 | CA12 (0.41) | RARGRARBHTTCFBTPMT | |
| SCHEMBL10933539 | 0.76 | CA12 (0.41) | RARGRARBHTTCFBTPMT | |
| SCHEMBL10937669 | 0.75 | RARG (0.53) | RARGRARBHTTTPMTCA12 | |
| SCHEMBL10936502 | 0.72 | RARG (0.43) | RARGRARBCA12CA1CA2 | |
| SCHEMBL10936516 | 0.72 | RARG (0.43) | RARGRARBCA12CA1CA2 | |
| SCHEMBL10186122 | 0.71 | CA12 (0.61) | HTTCFBTPMTCA12CA1 | |
| SCHEMBL1782019 | 0.71 | RARG (0.66) | RARGRARBCA12CA1CA2 | |
| SCHEMBL1422581 | 0.71 | RARG (0.66) | RARGRARBCA12CA1CA2 | |
| SCHEMBL1782039 | 0.71 | RARG (0.66) | RARGRARBCA12CA1CA2 | |
| SCHEMBL10936711 | 0.70 | RARG (0.54) | RARGRARBCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155940-A1 | BENZONORBORNENYL, BENZOPYRANYL AND BENZOTHIOPYRANYL RETINOIC ACID ANALOGUES | SRI INTERNATIONAL (US) | 1985-10-02 | — | — | EP | disclosed |
| WO-1985000806-A1 | BENZONORBORNENYL, BENZOPYRANYL AND BENZOTHIOPYRANYL RETINOIC ACID ANALOGUES | SRI INTERNATIONAL (US) | 1985-02-28 | — | — | WO | disclosed |