Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10935425 | 0.87 | ELANE (0.47) | ELANEMAPTMAPK1KDM4EMEN1 | |
| SCHEMBL10934437 | 0.83 | MEN1 (0.46) | ELANEMAPTMAPK1KDM4EMEN1 | |
| SCHEMBL30785050 | 0.76 | ELANE (0.48) | ELANEMAPTMAPK1KDM4EGAA | |
| SCHEMBL10935638 | 0.75 | MAPT (0.55) | ELANEMAPTMAPK1KDM4EMEN1 | |
| SCHEMBL10936326 | 0.75 | MAPT (0.49) | ELANEMAPTMAPK1KDM4EMEN1 | |
| SCHEMBL10935929 | 0.74 | TP53 (0.46) | ELANEMAPTMAPK1GAALMNA | |
| SCHEMBL25902691 | 0.73 | KMT2A (0.54) | MAPTMAPK1KDM4EMEN1USP2 | |
| SCHEMBL11638597 | 0.72 | MAPT (0.49) | MAPTKDM4EMEN1USP2GAA | |
| SCHEMBL10937430 | 0.72 | ELANE (0.57) | ELANEMAPTMAPK1GAAALDH1A1 | |
| SCHEMBL21486396 | 0.72 | POLB (0.50) | ELANEMAPTMAPK1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0085265-B1 | PROCESS FOR THE PREPARATION OF ALPHA,ALPHA-DIFLUOROALKOXY OR ALPHA,ALPHA-DIFLUOROALKYLTHIOPHENYL KETONES | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1985-05-22 | — | — | EP | disclosed |