Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 5/20 | 0.48 |
| ▸ | CA2 | P00918 | 5/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14347806 | 0.83 | TSHR (0.50) | TSHRCA1CA2CA9CA5A | |
| SCHEMBL7596921 | 0.81 | TSHR (0.48) | TSHRCA1CA2CA9CA5A | |
| SCHEMBL778852 | 0.77 | MAPK1 (0.44) | CA1CA2CA9CA5AALDH1A1 | |
| SCHEMBL752118 | 0.75 | CA1 (0.48) | TSHRCA1CA2CA9CA5A | |
| SCHEMBL27826304 | 0.73 | TSHR (0.71) | TSHRCA1CA2CA9CA5A | |
| SCHEMBL751741 | 0.73 | CA1 (0.47) | TSHRCA1CA2CA9CA5A | |
| SCHEMBL6025165 | 0.70 | TSHR (0.60) | TSHRCA1CA2CA9CA5A | |
| SCHEMBL15450593 | 0.70 | TSHR (0.60) | TSHRCA1CA2CA9CA5A | |
| SCHEMBL4617415 | 0.70 | GAA (0.70) | TSHRGAAALDH1A1MEN1KMT2A | |
| SCHEMBL14347810 | 0.70 | TSHR (0.46) | TSHRCA1CA2CA9CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4501704-A | Aromatic sulfonyl alkanoates and alkylnitriles | ROUSSEL UCLAF (FR) | 1985-02-26 | — | — | US | disclosed |
| US-4401601-A | Novel process for the preparation of tetra-substituted cyclopropane compounds | ROUSSEL UCLAF (FR) | 1983-08-30 | — | — | US | disclosed |