Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | FURIN | P09958 | 3/20 | 0.41 |
| ▸ | PCSK6 | P29122 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | NMT2 | O60551 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30185606 | 0.89 | FOLH1 (0.51) | ECE1NOD1FOLH1CPB2 | |
| SCHEMBL29355062 | 0.88 | ECE1 (0.50) | ECE1BACE1CTSDNOD1PDCD1LG2 | |
| SCHEMBL29612058 | 0.88 | FURIN (0.49) | BACE1CTSDFURINPCSK6PDCD1LG2 | |
| SCHEMBL31475710 | 0.87 | FURIN (0.43) | BACE1CTSDFURINPCSK6CTSL | |
| SCHEMBL29588623 | 0.86 | FURIN (0.47) | FURINNOD1FOLH1CTSLNMT2 | |
| SCHEMBL29784947 | 0.85 | NMT1 (0.48) | FURINPCSK6NOD1CPB2CTSL | |
| SCHEMBL31232968 | 0.85 | GNPAT (0.52) | ECE1NOD1FOLH1CPB2 | |
| SCHEMBL30081121 | 0.85 | NMT1 (0.46) | BACE1CTSDFURINPCSK6PDCD1LG2 | |
| SCHEMBL29630490 | 0.85 | NMT1 (0.46) | BACE1CTSDFURINPCSK6PDCD1LG2 | |
| SCHEMBL31129145 | 0.85 | BACE1 (0.46) | ECE1BACE1CTSDPDCD1LG2CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0067425-B1 | POSSIBLY PROTECTED PEPTIDES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL AGENTS CONTAINING THEM | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1985-09-18 | — | — | EP | disclosed |
| EP-0067425-A1 | Possibly protected peptides, process for their preparation and pharmaceutical agents containing them | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1982-12-22 | — | — | EP | disclosed |