Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | PREP | P48147 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8160094 | 0.80 | PREP (0.48) | NPC1RAB9ASMN1; SMN2PREPL3MBTL1 | |
| SCHEMBL12248057 | 0.79 | PREP (0.49) | NPC1RAB9ASMN1; SMN2PREPL3MBTL1 | |
| SCHEMBL11311747 | 0.78 | PREP (0.54) | NPC1RAB9ASMN1; SMN2PREPCYP2C19 | |
| SCHEMBL10712232 | 0.77 | KMT2A (0.44) | NPC1RAB9ASMN1; SMN2PREPL3MBTL1 | |
| SCHEMBL10714474 | 0.76 | SMN1; SMN2 (0.42) | NPC1RAB9ASMN1; SMN2PREPL3MBTL1 | |
| SCHEMBL5702006 | 0.75 | SMN1; SMN2 (0.61) | NPC1RAB9ASMN1; SMN2PREPCYP2C19 | |
| SCHEMBL4668774 | 0.75 | SMN1; SMN2 (0.61) | NPC1RAB9ASMN1; SMN2PREPCYP2C19 | |
| SCHEMBL3134513 | 0.75 | SMN1; SMN2 (0.61) | NPC1RAB9ASMN1; SMN2PREPCYP2C19 | |
| SCHEMBL3825810 | 0.75 | SMN1; SMN2 (0.56) | NPC1RAB9ASMN1; SMN2PREPCYP2C19 | |
| SCHEMBL3614576 | 0.75 | SMN1; SMN2 (0.56) | NPC1RAB9ASMN1; SMN2PREPCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8729077-B2 | Anti-viral compounds, compositions, and methods of use | GLAXOSMITHKLINE LLC (US) | 2014-05-20 | — | — | US | disclosed |
| WO-2010062821-A1 | ANTI-VIRAL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | GLAXOSMITHKLINE LLC (US) | 2010-06-03 | — | — | WO | disclosed |
| US-4511390-A | STIMULANT OF NUTRIENT UPTAKE IN PLANTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-04-16 | — | — | US | disclosed |