SCHEMBL10944856

SCHEMBL10944856

CC(Oc1ccc(Sc2ccc(C(F)(F)F)cc2)cc1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 5/20 0.56
PPARD Q03181 4/20 0.56
CYP1A2 P05177 1/20 0.50
GAA P10253 1/20 0.50
CYP2C9 P11712 1/20 0.50
PKM P14618 1/20 0.50
CYP2C19 P33261 1/20 0.50
PPARG P37231 4/20 0.48
TDP1 Q9NUW8 1/20 0.46
PDK2 Q15119 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
SLC6A9 P48067 1/20 0.41
PTGDR2 Q9Y5Y4 3/20 0.40
ABCB11 O95342 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11597291 0.91 CYP1A2 (0.59) PPARAPPARDCYP1A2GAACYP2C9
SCHEMBL25212758 0.91 CYP1A2 (0.59) PPARAPPARDCYP1A2GAACYP2C9
SCHEMBL21057241 0.91 CYP1A2 (0.59) PPARAPPARDCYP1A2GAACYP2C9
SCHEMBL13603783 0.87 GAA (0.62) PPARACYP1A2GAACYP2C9PKM
SCHEMBL136831 0.86 CYP1A2 (0.54) PPARAPPARDCYP1A2GAACYP2C9
SCHEMBL8089167 0.86 CYP1A2 (0.54) PPARAPPARDCYP1A2GAACYP2C9
SCHEMBL8089170 0.86 CYP1A2 (0.54) PPARAPPARDCYP1A2GAACYP2C9
Ammonia Solution, Strong SCHEMBL10963110 0.85 CYP1A2 (0.53) PPARAPPARDCYP1A2GAACYP2C9
Fluoride SCHEMBL10946418 0.85 CYP1A2 (0.53) PPARAPPARDCYP1A2GAACYP2C9
Hydrochloric Acid SCHEMBL10943650 0.85 CYP1A2 (0.53) PPARAPPARDCYP1A2GAACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4522647-A Substituted phenoxyalkanediones and their herbicidal method of use ZOECON CORPORATION (US) 1985-06-11 US disclosed
US-4500724-A REACTION OF ALKYL HALIDE WITH POWDERED SILICON USING COPPER-ZINE-TIN CATALYST GENERAL ELECTRIC COMPANY (US) 1985-02-19 US disclosed
US-4497965-A PRE-AND POSTEMERGENT HERBICIDES ZOECON CORPORATION (US) 1985-02-05 US disclosed
EP-0109483-A1 Substituted phenoxyalkane diones, intermediates for these compounds and the use of phenoxyalkane diones in the control of weeds ZOECON CORPORATION (US) 1984-05-30 EP disclosed
US-4448966-A HERBICIDES ZOECON CORPORATION (US) 1984-05-15 US disclosed