Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | CA7 | P43166 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6160950 | 0.88 | CA12 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31094175 | 0.88 | CA12 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL18502198 | 0.87 | CA12 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL19230590 | 0.85 | CA1 (0.68) | CA12CA1CA2CA7CA9 | |
| SCHEMBL20703389 | 0.85 | CA12 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4267597 | 0.85 | CA12 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9479617 | 0.85 | CA1 (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5738127 | 0.84 | CA12 (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6300062 | 0.84 | CA12 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1198863 | 0.84 | CA12 (0.53) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4532343-A | Aromatic retinoic acid analogues | SRI INTERNATIONAL (US) | 1985-07-30 | — | — | US | disclosed |