Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 8/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | MLX | Q9UH92 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10939797 | 1.00 | MEN1 (0.49) | MEN1KMT2AACEACE2XIAP | |
| SCHEMBL10939794 | 1.00 | MEN1 (0.49) | MEN1KMT2AACEACE2XIAP | |
| SCHEMBL10944882 | 1.00 | MEN1 (0.49) | MEN1KMT2AACEACE2XIAP | |
| SCHEMBL10942354 | 0.91 | ACE (0.49) | ACEACE2 | |
| SCHEMBL10940700 | 0.91 | ACE (0.49) | ACEACE2 | |
| SCHEMBL10942361 | 0.91 | ACE (0.49) | ACEACE2 | |
| SCHEMBL10940703 | 0.91 | ACE (0.49) | ACEACE2 | |
| SCHEMBL10940194 | 0.91 | ACE (0.49) | ACEACE2 | |
| SCHEMBL10940199 | 0.91 | ACE (0.49) | ACEACE2 | |
| SCHEMBL10942308 | 0.85 | ACE (0.50) | KMT2AACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0110225-B1 | BIS-(BENZOYLTHIO)-CARBOXYLIC ACIDS, THEIR PREPARATION AND USE IN THE PRODUCTION OF ACTIVE INGREDIENTS | BASF Aktiengesellschaft (DE) | 1985-10-23 | — | — | EP | disclosed |
| US-4500467-A | ANGIOTENSIN INHIBITORS, HYPOTENSIVE AGENTS | BASF AKTIENGESELLSCAFT (DE) | 1985-02-19 | — | — | US | disclosed |
| EP-0110224-A2 | Benzoylthio compounds, their manufacture and use as medicines | BASF Aktiengesellschaft (DE) | 1984-06-13 | — | — | EP | disclosed |
| EP-0110225-A1 | Bis-(benzoylthio)-carboxylic acids, their preparation and use in the production of active ingredients | BASF Aktiengesellschaft (DE) | 1984-06-13 | — | — | EP | disclosed |