Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.60 |
| ▸ | CNR2 | P34972 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.57 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.56 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.56 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.56 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.56 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.56 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.56 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.56 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.56 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.56 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.56 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.56 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.56 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.56 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.56 |
| ▸ | PSMB3 | P49720 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10946411 | 1.00 | TRPV1 (0.61) | TRPV1CNR1CNR2HPGDGPR119 | |
| SCHEMBL8375073 | 0.92 | TRPV1 (0.71) | TRPV1HPGDKDM4ELMNATP53 | |
| SCHEMBL8374584 | 0.92 | TRPV1 (0.71) | TRPV1HPGDKDM4ELMNATP53 | |
| SCHEMBL7271175 | 0.92 | TRPV1 (0.71) | TRPV1HPGDKDM4ELMNATP53 | |
| SCHEMBL7262810 | 0.92 | TRPV1 (0.71) | TRPV1HPGDKDM4ELMNATP53 | |
| SCHEMBL7268933 | 0.92 | TRPV1 (0.71) | TRPV1HPGDKDM4ELMNATP53 | |
| SCHEMBL10947025 | 0.92 | TRPV1 (0.71) | TRPV1HPGDKDM4ELMNATP53 | |
| SCHEMBL7263369 | 0.92 | TRPV1 (0.71) | TRPV1HPGDKDM4ELMNATP53 | |
| SCHEMBL7270390 | 0.92 | TRPV1 (0.71) | TRPV1HPGDKDM4ELMNATP53 | |
| SCHEMBL7268989 | 0.92 | TRPV1 (0.71) | TRPV1HPGDKDM4ELMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0089710-B1 | NOVEL HYDROXYPHENYLACETAMIDES HAVING ANALGESIC AND ANTI-IRRITANT ACTIVITY | THE PROCTER & GAMBLE COMPANY (US) | 1985-07-31 | — | — | EP | disclosed |
| US-4424205-A | DEPILLATORIES | THE PROCTER & GAMBLE COMPANY (US) | 1984-01-03 | — | — | US | disclosed |
| EP-0089710-A1 | Novel hydroxyphenylacetamides having analgesic and anti-irritant activity | THE PROCTER & GAMBLE COMPANY (US) | 1983-09-28 | — | — | EP | disclosed |