Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.63 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.63 |
| ▸ | P2RY10 | O00398 | 2/20 | 0.55 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.52 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.51 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.51 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.51 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.51 |
| ▸ | AKT1 | P31749 | 4/20 | 0.50 |
| ▸ | AKT2 | P31751 | 3/20 | 0.50 |
| ▸ | AKT3 | Q9Y243 | 3/20 | 0.50 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.50 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.48 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10948714 | 1.00 | LPAR3 (0.63) | LPAR3LPAR1P2RY10PLA2G2CLPAR6 | |
| SCHEMBL10952137 | 1.00 | LPAR3 (0.63) | LPAR3LPAR1P2RY10PLA2G2CLPAR6 | |
| SCHEMBL10952127 | 1.00 | LPAR3 (0.63) | LPAR3LPAR1P2RY10PLA2G2CLPAR6 | |
| SCHEMBL10950257 | 0.97 | LPAR1 (0.60) | LPAR3LPAR1P2RY10PLA2G2CLPAR6 | |
| SCHEMBL10950267 | 0.97 | LPAR1 (0.60) | LPAR3LPAR1P2RY10PLA2G2CLPAR6 | |
| SCHEMBL10951761 | 0.95 | LPAR3 (0.57) | LPAR3LPAR1P2RY10PLA2G2CLPAR6 | |
| SCHEMBL10950559 | 0.93 | LPAR1 (0.58) | LPAR3LPAR1PLA2G2CLPAR6LPAR4 | |
| SCHEMBL10954412 | 0.93 | LPAR1 (0.58) | LPAR3LPAR1PLA2G2CLPAR6LPAR4 | |
| SCHEMBL10951304 | 0.93 | LPAR1 (0.58) | LPAR3LPAR1PLA2G2CLPAR6LPAR4 | |
| SCHEMBL10565193 | 0.93 | LPAR1 (0.58) | LPAR3LPAR1PLA2G2CLPAR6LPAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4562005-A | ANTITUMOR | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-12-31 | — | — | US | disclosed |