Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10965571 | 0.86 | HSP90AA1 (0.54) | KMT2AMAPTPOLBCYP3A4ALDH1A1 | |
| SCHEMBL9871573 | 0.81 | CYP3A4 (0.52) | KMT2AHTTMAPTPOLBCYP3A4 | |
| SCHEMBL10390727 | 0.81 | TSHR (0.52) | KMT2AHTTMAPTPOLBCYP3A4 | |
| SCHEMBL6949649 | 0.78 | MAPT (0.48) | KMT2AHTTMAPTPOLBCYP3A4 | |
| SCHEMBL11350755 | 0.77 | CYP3A4 (0.48) | KMT2AHTTMAPTPOLBCYP3A4 | |
| SCHEMBL10680117 | 0.76 | MAPT (0.46) | KMT2AHTTMAPTPOLBCYP3A4 | |
| SCHEMBL11444256 | 0.76 | CYP3A4 (0.52) | KMT2AHTTMAPTPOLBCYP3A4 | |
| SCHEMBL11535584 | 0.76 | CYP3A4 (0.52) | KMT2AHTTMAPTPOLBCYP3A4 | |
| SCHEMBL27290860 | 0.75 | KMT2A (0.64) | KMT2AHTTMAPTPOLBCYP3A4 | |
| SCHEMBL1968152 | 0.75 | TSHR (0.47) | KMT2AMAPTPOLBCYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0061051-B1 | SUBSTITUTED TRIAZOLYLMETHYL OXIRANES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION AS INTERMEDIATES | BAYER AG (DE) | 1985-09-18 | — | — | EP | disclosed |
| US-4499281-A | AND PLANT GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1985-02-12 | — | — | US | disclosed |
| EP-0061051-A1 | Substituted triazolylmethyl oxiranes, process for their preparation and their application as intermediates | BAYER AG (DE) | 1982-09-29 | — | — | EP | disclosed |